Validation of multiple breath washout devices
نویسندگان
چکیده
منابع مشابه
Equipment for multiple breath washout.
5 Demeo DL, Campbell EJ, Barker AF, et al. IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency. We read with interest the article ''Paediatrics in Berlin'' [1] in a recent issue of the European Respiratory Journal, which sum-marised the paediatric topics of the European Respiratory Society's Annual Congress in Berlin. In this article, inert gas mul...
متن کاملValidation of multiple-breath washout equipment: from bench to clinic and possible pitfalls.
much more widely used, such as spirometry, body plethysmography or T L CO . Before results of MBW can be compared between centres or even multi-centre trials can be performed, these kinds of validation studies are extremely important to guarantee comparability and identify sources of errors. In this regard, Gonem et al. [15] are to be congratulated for the thorough validation study of the Innoc...
متن کاملA Realistic Validation Study of a New Nitrogen Multiple-Breath Washout System
BACKGROUND For reliable assessment of ventilation inhomogeneity, multiple-breath washout (MBW) systems should be realistically validated. We describe a new lung model for in vitro validation under physiological conditions and the assessment of a new nitrogen (N(2))MBW system. METHODS The N(2)MBW setup indirectly measures the N(2) fraction (F(N2)) from main-stream carbon dioxide (CO(2)) and si...
متن کاملIn vitro and in vivo functional residual capacity comparisons between multiple-breath nitrogen washout devices
Functional residual capacity (FRC) accuracy is essential for deriving multiple-breath nitrogen washout (MBNW) indices, and is the basis for device validation. Few studies have compared existing MBNW devices. We evaluated in vitro and in vivo FRC using two commercial MBNW devices, the Exhalyzer D (EM) and the EasyOne Pro LAB (ndd), and an in-house device (Woolcock in-house device, WIMR). FRC mea...
متن کاملImpact of Software Settings on Multiple-Breath Washout Outcomes
BACKGROUND AND OBJECTIVES Multiple-breath washout (MBW) is an attractive test to assess ventilation inhomogeneity, a marker of peripheral lung disease. Standardization of MBW is hampered as little data exists on possible measurement bias. We aimed to identify potential sources of measurement bias based on MBW software settings. METHODS We used unprocessed data from nitrogen (N2) MBW (Exhalyze...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cystic Fibrosis
سال: 2017
ISSN: 1569-1993
DOI: 10.1016/j.jcf.2017.01.011